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5–4 μmol/L variety,[156][157] the focus of serotonin in synaptic vesicles was calculated at 270 mM.[182] subsequent vesicular release, the ensuing focus of serotonin inside the synaptic cleft, to which serotonin receptors are exposed, is believed for being about 300 μmol/L. Therefore, though in vitro receptor binding affinities, efficacies, a
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